منابع مشابه
Evalution of HbA2 In Minor β Thalassemia Carriers Reffered to Kerman Special Disease Center
Increased HbA2 is a characteristic finding in minor beta thalassemia. Minor β-thalassemia is a heterozygote form of β-thalassemia that carries thalassemia genes but does not cause thalassemia disease. Diagnosis of carriers is done by CBC, RBC Index, and HbA2 test. Very few cases of people with minorthalassemia have a normal HbA2. According to the results of this pilot study it seams that percen...
متن کاملParkinsonism among Gaucher disease carriers.
An association between Gaucher disease and Parkinson disease has been demonstrated by the concurrence of Gaucher disease and parkinsonism in rare patients and the identification of glucocerebrosidase mutations in probands with sporadic Parkinson disease. Using a different and complementary approach, we describe 10 unrelated families of subjects with Gaucher disease where obligate or confirmed c...
متن کاملA Systems View of the Differences between APOE ε4 Carriers and Non-carriers in Alzheimer’s Disease
APOE ε4 is the strongest genetic risk factor for late-onset Alzheimer's disease (AD) and accounts for 50-65% of late-onset AD. Late-onset AD patients carrying or not carrying APOE ε4 manifest many clinico-pathological distinctions. Thus, we applied a weighted gene co-expression network analysis to identify specific co-expression modules in AD based on APOE ε4 stratification. Two specific module...
متن کاملmTOR: Alzheimer's disease prevention for APOE4 carriers
Alzheimer’s disease (AD) is the most common form of dementia and the 6th leading cause of death in the US. Inheritance of the Apolipoprotein ε4 (APOE4) allele is the strongest genetic risk factor for late-onset AD APOE4 carriers accumulate beta-amyloid (Aβ) and neurofibrillary tau tangles earlier and with more extensive pathology compared to non-carriers. However, decades before the aggregation...
متن کاملP 119: Role of Gut Bacteria on Alzheimer’s Disease
Alzheimer’s disease (AD) is a neurodegenerative disease that is the most common type of dementia.AD includes 60_80% of dementia and most people with AD have more than 65 years old.AD causes losing neuronal activity by abnormal proteins. Plaques of beta-amyloid and tangles of “tau” protein can lead to AD. Recently evidence has found that AD may come from outside of central nerv...
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ژورنال
عنوان ژورنال: Public Health
سال: 1911
ISSN: 0033-3506
DOI: 10.1016/s0033-3506(11)80047-8